MIST therapy is delivered by which method?

• A. Direct contact high frequency US through a gel pad
• B. Non-contact low frequency US (30-40 kHz) delivered through a saline mist to stimulate cells in and under the wound bed
• C. Laser-assisted thermal therapy through saline spray
• D. Standard acoustic US with direct skin contact

Answer: (B)

MIST therapy delivers ultrasound energy in a non-contact way, using a fine saline mist as the coupling medium to carry low-frequency energy to the wound bed. The energy is typically around 30–40 kHz and is applied without touching the wound, so it mechanically stimulates cells in and underneath the wound bed without the heating or direct contact associated with conventional ultrasound. This non-contact, low-frequency approach helps promote cellular activity, granulation, and healing while minimizing disruption of the wound surface.

That’s why this option is the best fit: it describes non-contact delivery through a saline mist at a low frequency, rather than direct-contact high-frequency ultrasound, laser-based therapy, or standard contact ultrasound.